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Original Research

A comparison of radiological tumor size and pathologic tumor size in renal cell carcinoma


Dr. Abdurrahman Yurtaslan Ankara Onkoloji Eğitim ve Araştırma Hastanesi Üroloji Kliniği


DOI :
New J Urol. 2016; 11 (1): 10-13

Abstract

Objective: Tumor size in kidney tumor is an important prognostic factor in determining the tre-atment. In our study, the difference between radiog-raphic tumor size (RTS) and pathologic tumor size (PTS) in patients who undergoing surgery for renal cell carcinoma has been investigated. The compa-rison has been also made according to histological subtypes.

Materials and Methods: One hundred and five patients who undergoing surgery due to renal cell carcinomas were evaluated retrospectively between September 2010 and March 2015. Baseline charac-teristics of patients such as age, sex, type of surgery, pathological T stage, RTS and PTS, tumor location and histologic subtype were investigated. Radiog-raphic and pathologic tumor size, histological subt-ypes and radiological examinations were compared. Statistical analysis was performed by Pearson’s chi-square test.

Results: For all patients, the mean RTS and PTS was 40.1 mm (19-150 mm) and 42.3 mm (12-180 mm), respectively. When we grouped patients according to tumor size, PTS <4 cm cases had signi-ficant statistically results (p <0.05). For a PTS of 4-7 cm, the mean RTS was smaller than the mean PTS (47.4 ve 55.7 mm, p=0.35), however for a PTS > 7 cm patients had similar results (86.9 ve 91.2 mm, p=0.15). Among patients with clear cell carcino-mas, the mean RTS was significantly larger than the mean PTS (39.7 mm and 38.9 mm, p<0.05 respec-tively), not for non clear cell group (38.1 mm and 48.9 mm, p=0.4 respectively).

Conclusion: Renal tumors can be high mea-sured radiologically, especially the tumor size is <4 cm. low measured when renal masses are > 4cm. So it should not be decided choice of nephron sparing surgery or radical nephrectomy just looking at the tumor size.

Key Words: kidney neoplasms, renal cell carci-nomas, radiological tumor size, pathological tumor size


Abstract

Objective: Tumor size in kidney tumor is an important prognostic factor in determining the tre-atment. In our study, the difference between radiog-raphic tumor size (RTS) and pathologic tumor size (PTS) in patients who undergoing surgery for renal cell carcinoma has been investigated. The compa-rison has been also made according to histological subtypes.

Materials and Methods: One hundred and five patients who undergoing surgery due to renal cell carcinomas were evaluated retrospectively between September 2010 and March 2015. Baseline charac-teristics of patients such as age, sex, type of surgery, pathological T stage, RTS and PTS, tumor location and histologic subtype were investigated. Radiog-raphic and pathologic tumor size, histological subt-ypes and radiological examinations were compared. Statistical analysis was performed by Pearson’s chi-square test.

Results: For all patients, the mean RTS and PTS was 40.1 mm (19-150 mm) and 42.3 mm (12-180 mm), respectively. When we grouped patients according to tumor size, PTS <4 cm cases had signi-ficant statistically results (p <0.05). For a PTS of 4-7 cm, the mean RTS was smaller than the mean PTS (47.4 ve 55.7 mm, p=0.35), however for a PTS > 7 cm patients had similar results (86.9 ve 91.2 mm, p=0.15). Among patients with clear cell carcino-mas, the mean RTS was significantly larger than the mean PTS (39.7 mm and 38.9 mm, p<0.05 respec-tively), not for non clear cell group (38.1 mm and 48.9 mm, p=0.4 respectively).

Conclusion: Renal tumors can be high mea-sured radiologically, especially the tumor size is <4 cm. low measured when renal masses are > 4cm. So it should not be decided choice of nephron sparing surgery or radical nephrectomy just looking at the tumor size.

Key Words: kidney neoplasms, renal cell carci-nomas, radiological tumor size, pathological tumor size