Objectives: Erectile Dysfunction (ED) is an important problem that decreases the qua-lity of life all over the world. In addition, it is an important health problem because it occurs as a result of systemic diseases and/or it is a precur-sor of some of the complications of systemic di-seases. In this study, we aim to determine the most important etiologic risk factors in patients with a diagnosis of organic ED.
Material and Methods: A total of 273 male patients with a clinical diagnosis of organic ED from andrology outpatient clinics and 110 age-matched control group with any reason except the ED from general urology outpatient clinics enrolled in this study at Istanbul Medeniyet Universty Faculty of Medicine. Physical exami-nation, medical history, the International In-dex of Erectile Function Questionnaire (IIEF-5) scores and laboratory findings of all patients have been examined. The importance of risk factors ( smoking, hyperlipidemia (HL), hyper-tension (HT), diabetes mellitus (DM), coro-nary artery disease (CAD), previous pelvic sur-gery predisposing to ED have been identified via univariate and multivariate analysis models.
Results: Smoking, HL, HT, DM, CAD, and previous pelvic surgery were found to be a statistically significant risk factors for ED in the univariate model (p<0.05, for each fac-tors). But in multivariate model smoking, DM and previous pelvic surgery were found to be a statistically signifi-cant risk factors for ED. The affect of smoking, HT, DM, HL on IIEF scores and serum testosterone levels were studied and we obser-ved that althought HT, DM, smoking significantly decrease IIEF scores(p<0.005), HL does not show statistically significant effect on IIEF scores. Serum testosterone level was not affected by any of these factors.
Conclusion: In addition to the previous pelvic surgery, the most important risk factors for organic erectile dysfunction are smoking and diabetes mellitus.
Key Words: organic erectile dysfunction, risk factors, iief-5
Abstract
Objectives: Erectile Dysfunction (ED) is an important problem that decreases the qua-lity of life all over the world. In addition, it is an important health problem because it occurs as a result of systemic diseases and/or it is a precur-sor of some of the complications of systemic di-seases. In this study, we aim to determine the most important etiologic risk factors in patients with a diagnosis of organic ED.
Material and Methods: A total of 273 male patients with a clinical diagnosis of organic ED from andrology outpatient clinics and 110 age-matched control group with any reason except the ED from general urology outpatient clinics enrolled in this study at Istanbul Medeniyet Universty Faculty of Medicine. Physical exami-nation, medical history, the International In-dex of Erectile Function Questionnaire (IIEF-5) scores and laboratory findings of all patients have been examined. The importance of risk factors ( smoking, hyperlipidemia (HL), hyper-tension (HT), diabetes mellitus (DM), coro-nary artery disease (CAD), previous pelvic sur-gery predisposing to ED have been identified via univariate and multivariate analysis models.
Results: Smoking, HL, HT, DM, CAD, and previous pelvic surgery were found to be a statistically significant risk factors for ED in the univariate model (p<0.05, for each fac-tors). But in multivariate model smoking, DM and previous pelvic surgery were found to be a statistically signifi-cant risk factors for ED. The affect of smoking, HT, DM, HL on IIEF scores and serum testosterone levels were studied and we obser-ved that althought HT, DM, smoking significantly decrease IIEF scores(p<0.005), HL does not show statistically significant effect on IIEF scores. Serum testosterone level was not affected by any of these factors.
Conclusion: In addition to the previous pelvic surgery, the most important risk factors for organic erectile dysfunction are smoking and diabetes mellitus.
Key Words: organic erectile dysfunction, risk factors, iief-5