Objective: The aim of this study is to compa-re the clinical features of the patients with a be-nign pathologic report who underwent radical or partial nephrectomy with a preliminary diagnosis of renal mass with the malignant ones.
Material and Methods: Between January 2001 and April 2013, 406 patients who underwent surgery in our clinic with a preliminary diagno-sis of renal tumor were evaluated retrospectively. Two groups of 54 patients with a benign diagno-sis (Group 1) and 352 patients with a malignant diagnosis (Group 2) were formed based on his-topathological examination results. For patholo-gical staging 2010 TNM staging system and for histological subtype classification 2004 WHO classification were used. The longest diameter from those measured from pathological speci-mens were presumed as tumor size. All patients were reviewed according to age, sex, symptoms at diagnosis, multifocality, tumor size and histo-logical subtypes.
Results: The mean age of the patients was 58.3±5.29 (46-58) in the benign group, where-as 63.5±8.17 (42-83) in the malignant group. 10 patients in the benign group (18%) were while the remaining 44 (82%) patients were detected incidentally. In the malignant group, 277 (79%) patients were applied symptomatically and 75 (21%) patients were detected incidentally. Multi-focality was observed in 2 patients in Group 1 (0.03%) and in 76 patients in group 2 (21%). In group 1 and group 2, the mean tumor diameter were 3.8 cm and 6.4 cm respectively. Statistically significant difference was detected in the presence of symptoms at diagnosis, multifocality and tumor size between two groups (p<0.05).
Conclusions: As well as previous studies, our study revealed that patients who underwent nephrectomy with a preliminary di-agnosis of renal mass whose pathology report came as malignant were symptomatic, multifocal and larger tumor sizes compared to benign ones.
Key Words: benign lesions, nephrectomy, renal mass
Abstract
Objective: The aim of this study is to compa-re the clinical features of the patients with a be-nign pathologic report who underwent radical or partial nephrectomy with a preliminary diagnosis of renal mass with the malignant ones.
Material and Methods: Between January 2001 and April 2013, 406 patients who underwent surgery in our clinic with a preliminary diagno-sis of renal tumor were evaluated retrospectively. Two groups of 54 patients with a benign diagno-sis (Group 1) and 352 patients with a malignant diagnosis (Group 2) were formed based on his-topathological examination results. For patholo-gical staging 2010 TNM staging system and for histological subtype classification 2004 WHO classification were used. The longest diameter from those measured from pathological speci-mens were presumed as tumor size. All patients were reviewed according to age, sex, symptoms at diagnosis, multifocality, tumor size and histo-logical subtypes.
Results: The mean age of the patients was 58.3±5.29 (46-58) in the benign group, where-as 63.5±8.17 (42-83) in the malignant group. 10 patients in the benign group (18%) were while the remaining 44 (82%) patients were detected incidentally. In the malignant group, 277 (79%) patients were applied symptomatically and 75 (21%) patients were detected incidentally. Multi-focality was observed in 2 patients in Group 1 (0.03%) and in 76 patients in group 2 (21%). In group 1 and group 2, the mean tumor diameter were 3.8 cm and 6.4 cm respectively. Statistically significant difference was detected in the presence of symptoms at diagnosis, multifocality and tumor size between two groups (p<0.05).
Conclusions: As well as previous studies, our study revealed that patients who underwent nephrectomy with a preliminary di-agnosis of renal mass whose pathology report came as malignant were symptomatic, multifocal and larger tumor sizes compared to benign ones.
Key Words: benign lesions, nephrectomy, renal mass