Objective: We aimed to reveal the rate of benign testicular pathologies detected in pa-tients who underwent radical orchiectomy and to guide clinicians in the differentiation of be-nign / malignant testicular masses.
Materials and Methods: The data of pa-tients who underwent radical orchiectomy op-eration between 2008-2018 were retrospectively reviewed. The parameters examined were de-mographic information of the patients, preop-erative serum tumor markers, scrotal imaging results and final pathology results.
Results: A total of 171 patients were in-cluded in the study. The mean age of the patients was 35.4 ± 13.6 years. According to the final pathology report, benign testicular pathology was found in 29 patients (17%) and malignancy was found in 142 patients (83%). The preopera-tive AFP, β-HCG and LDH values of the group with benign pathology were significantly lower than the group with malignant pathology: 2.03 ± 1.8 IU / mL, 0.32 ± 0.44 mIU / mL, and 157.3 ± 163.5 U / L compared to 335.5 ± 1490.7 IU / mL, 4045.9 ± 24444.7 mIU / mL, 423 ± 1089.2 U / L (p < .001 for all variables). In the preopera-tive USG examination of the group with benign pathology, the size of the mass in the testis was 3.02 ± 2.2 cm while the malignant group was 4.9 ± 2.5 cm (p = 0.006).
Conclusion: It is important to consider that small, non palpable testicular lesions don’t cause elevated serum tumor markers in patients outside the 15-34 age range, in which testicular tumors are frequent, may be highly benign and testis preserving surgery should be planned if necessary.
Keywords: testicular tumor, orchiectomy, testis sparing surgery
Abstract
Objective: We aimed to reveal the rate of benign testicular pathologies detected in pa-tients who underwent radical orchiectomy and to guide clinicians in the differentiation of be-nign / malignant testicular masses.
Materials and Methods: The data of pa-tients who underwent radical orchiectomy op-eration between 2008-2018 were retrospectively reviewed. The parameters examined were de-mographic information of the patients, preop-erative serum tumor markers, scrotal imaging results and final pathology results.
Results: A total of 171 patients were in-cluded in the study. The mean age of the patients was 35.4 ± 13.6 years. According to the final pathology report, benign testicular pathology was found in 29 patients (17%) and malignancy was found in 142 patients (83%). The preopera-tive AFP, β-HCG and LDH values of the group with benign pathology were significantly lower than the group with malignant pathology: 2.03 ± 1.8 IU / mL, 0.32 ± 0.44 mIU / mL, and 157.3 ± 163.5 U / L compared to 335.5 ± 1490.7 IU / mL, 4045.9 ± 24444.7 mIU / mL, 423 ± 1089.2 U / L (p < .001 for all variables). In the preopera-tive USG examination of the group with benign pathology, the size of the mass in the testis was 3.02 ± 2.2 cm while the malignant group was 4.9 ± 2.5 cm (p = 0.006).
Conclusion: It is important to consider that small, non palpable testicular lesions don’t cause elevated serum tumor markers in patients outside the 15-34 age range, in which testicular tumors are frequent, may be highly benign and testis preserving surgery should be planned if necessary.
Keywords: testicular tumor, orchiectomy, testis sparing surgery