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Original Research

Clinical results of patients with primary bladder cancer inside the diverticula


1 Haydarpaşa Sultan Abdülhamid Eğitim ve Araştırma Hastanesi, Üroloji Kliniği, İstanbul

2 Nevşehir Devlet Hastanesi, Üroloji Kliniği, Nevşehir

3 Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi, İstanbul


DOI :
New J Urol. 2017; 12 (2): 21-24

Abstract

Abstract

Objective: In this study, we examined the clinical courses of bladder tumors primary de-tected in a vesicular diverticulum.

Materials and Methods: We retrospec-tively examined our clinical data between 2006-2015 and 8 patients has diagnosed primary blad-der cancer within a vesicular diverticulum. All diagnosis were made with cystoscopic examina-tion. After the diagnosis CT or MRI was done for the staging. Initially transurethral resection of bladder tumour with subsequent intravesi-cal chemoterapy mitomycin\epirubicine was applied. According to the pathological results, if needed intravesical chemoterapy / immuno-therapy was given in the follow up.

Results: In our study diverticular blad-der cancer patients generally presented to the urology service with hematuria and they were incidentally detected with USG while they were evaluating for bladder outlet obstruction.  The majority of tumors detected in diverticula were <3cm and half was fixed in one focus. Obstruc-tive prostate lobes were seen in all patients and in the follow-up period ‘s additional prostate surgery  has been applied in 40% of the patients. Primary tumor pathology was reported as pTa low garde in 87.5% of the patients. In 62.5% of patients recurrence was found in the same di-verticulum or in other locations of the bladder). In follow-up period intravesical chemotherapy was applied in  37.5% of the patients, 25% re-ceived treatment with immunotherapy. Af-ter the first surgery no recurrence was seen in 37.5% of patients. None of the patients showed  stage progression. In one patient grade progres-sion was seen who had disease recurrence .

Conclusion: According to our current data, bladder tumors in the diverticulum tend to be small and low grade.

Keywords: Bladder tumor; diverticulum


Abstract

Abstract

Objective: In this study, we examined the clinical courses of bladder tumors primary de-tected in a vesicular diverticulum.

Materials and Methods: We retrospec-tively examined our clinical data between 2006-2015 and 8 patients has diagnosed primary blad-der cancer within a vesicular diverticulum. All diagnosis were made with cystoscopic examina-tion. After the diagnosis CT or MRI was done for the staging. Initially transurethral resection of bladder tumour with subsequent intravesi-cal chemoterapy mitomycin\epirubicine was applied. According to the pathological results, if needed intravesical chemoterapy / immuno-therapy was given in the follow up.

Results: In our study diverticular blad-der cancer patients generally presented to the urology service with hematuria and they were incidentally detected with USG while they were evaluating for bladder outlet obstruction.  The majority of tumors detected in diverticula were <3cm and half was fixed in one focus. Obstruc-tive prostate lobes were seen in all patients and in the follow-up period ‘s additional prostate surgery  has been applied in 40% of the patients. Primary tumor pathology was reported as pTa low garde in 87.5% of the patients. In 62.5% of patients recurrence was found in the same di-verticulum or in other locations of the bladder). In follow-up period intravesical chemotherapy was applied in  37.5% of the patients, 25% re-ceived treatment with immunotherapy. Af-ter the first surgery no recurrence was seen in 37.5% of patients. None of the patients showed  stage progression. In one patient grade progres-sion was seen who had disease recurrence .

Conclusion: According to our current data, bladder tumors in the diverticulum tend to be small and low grade.

Keywords: Bladder tumor; diverticulum

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