Objectives: In this study we aimed to compare the outcomes of nephrone sparing surgery (NSS) and radical nephrectomy (RN) on renal masses smaller than 7 cm.
Materials and Meth ods: Eighty-six patients treated by surgery, with renal masses smaller than 7 cm were evaluated retrospectively. There were thirty patients (17 male, 13 female) in the first group who underwent NSS, and fifty-six patients (31 male, 25 female) in the second group who underwent RN. After histopathological eva-luation, renal cell carcinoma (RCC) was detected in 22 patients in first group while RCC was detected 54 patients in second group and these patients were analyzed. Age, follow-up, mean tumour di-mater, stage, histopathology, preoperative and postoperative serum creatinine levels and survival were compared between the groups.
Results: While final pathological examination demonstrated 22 (73.3%) RCC, 7 (23.3%) benign pathology and 1 (3.3%) metasta-tic cancer in first group, 54 RCC (96.4%) and 2 (3.6%) benign pat-hology was demonstrated in second group. Mean age in NSS gro-up was 56.33±13.18 years and in RN group was 66.63± 11.65 years (P<0.001). Average follow-up period was 34.94±38.56 months and 42.31±37.76 months in NSS and RN groups respectively (p=0.529). Significant increase in postoperative serum creatinin levels was ob-served in RN patients (p= 0.031), but no such difference was obser-ved in NSS patients (p= 0.872). Five year overall survival rates were 100% for NSS group and 91.2% for RN group respectively (p= 0.227).
Conclusion: We suggest NSS in kidney tumors up to 7 cm di-ameter because of preservation of renal function, similar oncologi-cal outcomes compared with RN and definitive diagnosis of benign and malignant tumours.
Key Words: Renal mass; nephrone sparing surgery; radical nephrectomy.
Abstract
Objectives: In this study we aimed to compare the outcomes of nephrone sparing surgery (NSS) and radical nephrectomy (RN) on renal masses smaller than 7 cm.
Materials and Meth ods: Eighty-six patients treated by surgery, with renal masses smaller than 7 cm were evaluated retrospectively. There were thirty patients (17 male, 13 female) in the first group who underwent NSS, and fifty-six patients (31 male, 25 female) in the second group who underwent RN. After histopathological eva-luation, renal cell carcinoma (RCC) was detected in 22 patients in first group while RCC was detected 54 patients in second group and these patients were analyzed. Age, follow-up, mean tumour di-mater, stage, histopathology, preoperative and postoperative serum creatinine levels and survival were compared between the groups.
Results: While final pathological examination demonstrated 22 (73.3%) RCC, 7 (23.3%) benign pathology and 1 (3.3%) metasta-tic cancer in first group, 54 RCC (96.4%) and 2 (3.6%) benign pat-hology was demonstrated in second group. Mean age in NSS gro-up was 56.33±13.18 years and in RN group was 66.63± 11.65 years (P<0.001). Average follow-up period was 34.94±38.56 months and 42.31±37.76 months in NSS and RN groups respectively (p=0.529). Significant increase in postoperative serum creatinin levels was ob-served in RN patients (p= 0.031), but no such difference was obser-ved in NSS patients (p= 0.872). Five year overall survival rates were 100% for NSS group and 91.2% for RN group respectively (p= 0.227).
Conclusion: We suggest NSS in kidney tumors up to 7 cm di-ameter because of preservation of renal function, similar oncologi-cal outcomes compared with RN and definitive diagnosis of benign and malignant tumours.
Key Words: Renal mass; nephrone sparing surgery; radical nephrectomy.