Objective: In this study, we aimed to compare the success and complication rates of percutane- ous nephrolithotomy (PCNL) according to pre- operative glomerular filtration rates (GFR) of pa- tients who underwent PCNLdue to kidney stones.
Material and Methods: Between January 2012 and December 2016, 794 patients who un- derwent PCNL due to kidney Stones were evalu- ated retrospectively. Preoperative GFR values of patients were calculated according to Cockcroft–Gault formula. The patients with preoperative GFR values>90 ml/min, 60-90 ml/min, 30-60 ml/ min were respectively defined as group-1, group-2 and group-3. Preoperative and perioperative val- ues, Stone free rates and complication rates were compared between the groups. Postoperatively , <4 mm residual stone was identified as success.
Results: There were 466 patients in Group-1, 259 in Group-2 and 67 patients in Group-3. The mean preoperative GFR values of the pa- tients were 118.53 ml/min, 77.76 ml/min and 48.52 ml/min, respectively in group-1, group-2 and group-3 (p <0.001).The mean age of the patients was 62.8±11.47, 51.86±11.10, and60.31±12.7, respectively, in group-1, group-2 and group-3 (p<0.001).The mean Stone burden of the patients were 497.34±518.60 mm2, 517.6±493.8 mm2and 711.06±679.07 mm2, respectively, in group-1, group-2 and group-3 (p=0.013). The number of patients identified with success after surgery was 355 (86.2%), 195 (76.1%) and 50 (74.6%) in group-1, group-2 and group-3, respective- ly (p = 0.542). The number of patients who develop complications was 114 (%24.65), 57 (%22) and 11 (%16.4) in group-1, group-2 and group-3, respectively (p=0.310).
Conclusion: Preoperative GFR valuesare not lonely sufficient to predict success and complications after PCNL.
Keywords: Percutaneous nephrolithotomy, renal function, renal stone, glomerular filtration rates
ABSTRACT
Objective: In this study, we aimed to compare the success and complication rates of percutane- ous nephrolithotomy (PCNL) according to pre- operative glomerular filtration rates (GFR) of pa- tients who underwent PCNLdue to kidney stones.
Material and Methods: Between January 2012 and December 2016, 794 patients who un- derwent PCNL due to kidney Stones were evalu- ated retrospectively. Preoperative GFR values of patients were calculated according to Cockcroft–Gault formula. The patients with preoperative GFR values>90 ml/min, 60-90 ml/min, 30-60 ml/ min were respectively defined as group-1, group-2 and group-3. Preoperative and perioperative val- ues, Stone free rates and complication rates were compared between the groups. Postoperatively , <4 mm residual stone was identified as success.
Results: There were 466 patients in Group-1, 259 in Group-2 and 67 patients in Group-3. The mean preoperative GFR values of the pa- tients were 118.53 ml/min, 77.76 ml/min and 48.52 ml/min, respectively in group-1, group-2 and group-3 (p <0.001).The mean age of the patients was 62.8±11.47, 51.86±11.10, and60.31±12.7, respectively, in group-1, group-2 and group-3 (p<0.001).The mean Stone burden of the patients were 497.34±518.60 mm2, 517.6±493.8 mm2and 711.06±679.07 mm2, respectively, in group-1, group-2 and group-3 (p=0.013). The number of patients identified with success after surgery was 355 (86.2%), 195 (76.1%) and 50 (74.6%) in group-1, group-2 and group-3, respective- ly (p = 0.542). The number of patients who develop complications was 114 (%24.65), 57 (%22) and 11 (%16.4) in group-1, group-2 and group-3, respectively (p=0.310).
Conclusion: Preoperative GFR valuesare not lonely sufficient to predict success and complications after PCNL.
Keywords: Percutaneous nephrolithotomy, renal function, renal stone, glomerular filtration rates