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Original Research

Effect of Renal Function Reserve on Results of Percutaneous Nephrolithotomy


1 HSU Izmir Bozyaka Training and Research Hospital, Department of Urology, Izmir, Turkey
2 Dr. Yasar Eryilmaz Dogubayazit State Hospital, Department of Urology, Agri, Turkey 
3 Mustafa Kemalpaşa Central Hospital, Department of Urology, Bursa, Turkey
4 Amasya University Faculty of Medicine, Department of Urology, Amasya, Turkey
 


DOI : 10.33719/yud.2021;16-1-748024
New J Urol. 2021;16(1): 68-73

ABSTRACT

Objective: In this study, we aimed to compare the success and complication rates of percutane- ous nephrolithotomy (PCNL) according to pre- operative glomerular filtration rates (GFR) of pa- tients who underwent PCNLdue to kidney stones.

Material and Methods: Between January 2012 and December 2016, 794 patients who un- derwent PCNL due to kidney Stones were evalu- ated retrospectively. Preoperative GFR values of patients were calculated according to Cockcroft–Gault formula. The patients with preoperative GFR values>90 ml/min, 60-90 ml/min, 30-60 ml/ min were respectively defined as group-1, group-2 and group-3. Preoperative and perioperative val- ues, Stone free rates and complication rates were compared between the groups. Postoperatively , <4 mm residual stone was identified as success.

Results: There were 466 patients in Group-1, 259 in Group-2 and 67 patients in Group-3. The mean preoperative GFR values of the pa- tients were 118.53 ml/min, 77.76 ml/min and 48.52 ml/min, respectively in group-1, group-2 and group-3 (p <0.001).The mean age of the patients was  62.8±11.47,  51.86±11.10, and60.31±12.7, respectively, in group-1, group-2 and group-3 (p<0.001).The mean Stone burden of the patients were 497.34±518.60 mm2, 517.6±493.8 mm2and 711.06±679.07 mm2, respectively, in group-1, group-2 and group-3 (p=0.013). The number of patients identified with success after surgery was 355 (86.2%), 195 (76.1%) and 50 (74.6%) in group-1, group-2 and group-3, respective- ly (p = 0.542). The number of patients who develop complications was 114 (%24.65), 57 (%22) and 11 (%16.4) in group-1, group-2 and group-3, respectively (p=0.310).

Conclusion: Preoperative GFR valuesare not lonely sufficient to predict success and complications after PCNL.

Keywords: Percutaneous nephrolithotomy, renal function, renal stone, glomerular filtration rates


ABSTRACT

Objective: In this study, we aimed to compare the success and complication rates of percutane- ous nephrolithotomy (PCNL) according to pre- operative glomerular filtration rates (GFR) of pa- tients who underwent PCNLdue to kidney stones.

Material and Methods: Between January 2012 and December 2016, 794 patients who un- derwent PCNL due to kidney Stones were evalu- ated retrospectively. Preoperative GFR values of patients were calculated according to Cockcroft–Gault formula. The patients with preoperative GFR values>90 ml/min, 60-90 ml/min, 30-60 ml/ min were respectively defined as group-1, group-2 and group-3. Preoperative and perioperative val- ues, Stone free rates and complication rates were compared between the groups. Postoperatively , <4 mm residual stone was identified as success.

Results: There were 466 patients in Group-1, 259 in Group-2 and 67 patients in Group-3. The mean preoperative GFR values of the pa- tients were 118.53 ml/min, 77.76 ml/min and 48.52 ml/min, respectively in group-1, group-2 and group-3 (p <0.001).The mean age of the patients was  62.8±11.47,  51.86±11.10, and60.31±12.7, respectively, in group-1, group-2 and group-3 (p<0.001).The mean Stone burden of the patients were 497.34±518.60 mm2, 517.6±493.8 mm2and 711.06±679.07 mm2, respectively, in group-1, group-2 and group-3 (p=0.013). The number of patients identified with success after surgery was 355 (86.2%), 195 (76.1%) and 50 (74.6%) in group-1, group-2 and group-3, respective- ly (p = 0.542). The number of patients who develop complications was 114 (%24.65), 57 (%22) and 11 (%16.4) in group-1, group-2 and group-3, respectively (p=0.310).

Conclusion: Preoperative GFR valuesare not lonely sufficient to predict success and complications after PCNL.

Keywords: Percutaneous nephrolithotomy, renal function, renal stone, glomerular filtration rates