Aim: In this study we aimed to determi-ne the status of the neutrophil lymphocyte ratios of the new ISUP Gleason groups.
Material and Methods: Patients who underwent transrectal ultrasound-guided prostate biopsy and who had pathologically proven prostate cancer were evaluated retros-pectively. Neutrophil / lymphocyte ratios of all patients were determined. Their age, PSA values and body mass index (BMI) were re-corded. Patients were assigned to 5 Gleason groups according to ISUP 2014 definition. N / L ratios and other demographic data of the groups were compared with each other.
Results: Data from 86 patients meeting the study criteria were recorded. N/L ratios were found as 2.13 (0.27-9.28) in group 1, 2.22 (0.27-1.52) in group 2, 2.40 (1.41-6.30) in group 3, 1.90 (0.91-2.99) in group 4 and 2.11 (0.27-3.62) in group 5 (p=0.74).
Conclusion: N / L ratio was found to be similar in all Gleason groups according to present study. Prospective studies with large patient populations are needed to determine whether N / L ratio is a prognostic factor in localized PCa patients or not.
Key Words: Gleason score, neutrophil to lymphocyte ratio, prostate cancer
Abstract
Aim: In this study we aimed to determi-ne the status of the neutrophil lymphocyte ratios of the new ISUP Gleason groups.
Material and Methods: Patients who underwent transrectal ultrasound-guided prostate biopsy and who had pathologically proven prostate cancer were evaluated retros-pectively. Neutrophil / lymphocyte ratios of all patients were determined. Their age, PSA values and body mass index (BMI) were re-corded. Patients were assigned to 5 Gleason groups according to ISUP 2014 definition. N / L ratios and other demographic data of the groups were compared with each other.
Results: Data from 86 patients meeting the study criteria were recorded. N/L ratios were found as 2.13 (0.27-9.28) in group 1, 2.22 (0.27-1.52) in group 2, 2.40 (1.41-6.30) in group 3, 1.90 (0.91-2.99) in group 4 and 2.11 (0.27-3.62) in group 5 (p=0.74).
Conclusion: N / L ratio was found to be similar in all Gleason groups according to present study. Prospective studies with large patient populations are needed to determine whether N / L ratio is a prognostic factor in localized PCa patients or not.
Key Words: Gleason score, neutrophil to lymphocyte ratio, prostate cancer