Objective: To determine the ratios of Multi- drug resistance infection(MDRI) among the pathogens causing urinary infection and sepsis after percutaneous nephrolithotomy (PCNL).
Material and Method: After approval of the local ethics committee, the files of the patients who underwent PCNL between January 2013 and July 2017 and the urine culture results ob- tained were evaluated prospectively in our urol- ogy clinic. Pre-op urine culture, intraoperative renal puncture culture, stone washing culture and stone cultures were examined. Demographic characteristics of the patients and microorgan- isms breeding in all cultures were evaluated. In addition, the ratios of MDRI in microorganisms breeding in all four cultures and the factors that may cause it were evaluated statistically.
Results: Our study consisted of 155 patients, 78 of whom were male and 77 were female, with a mean age of 40.8 ± 16.6 years. While 88 of these patients’ stones were on the left and 67 were on the right, the average stone load of the patients was calculated to be 3827,74 ± 1932,07 mm3. When the urine culture results of the patients were examined, it was found that middle stream urine culture was observed in 34 patients (21.9%) in intrarenal urine culture in 57 patients (36.7%), in 24 patients (15.4%) in stone washing culture and in 21 patients in stone culture (13.5%). A total of eight patients (5.1%) had fever (0.69%) in only one of these patients. No statistically sig- nificant difference was found between the four cultures for the MDRI study (p> 0.05). When the factors that may cause MDRI are examined; we found that only male gender was a risk factor for MDRI.
Conclusion: It was concluded that male sex in patients with PCNL due to renal calculi is a risk factor for MDRI and that no additional treat- ment is needed when appropriate prophylactic and empirical treatment of MDRI is considered as a risk factor for postoperative fever and sepsis.
Keywords: Kidney stone; urinary infection; percutaneous nephrolithotomy
Abstract
Objective: To determine the ratios of Multi- drug resistance infection(MDRI) among the pathogens causing urinary infection and sepsis after percutaneous nephrolithotomy (PCNL).
Material and Method: After approval of the local ethics committee, the files of the patients who underwent PCNL between January 2013 and July 2017 and the urine culture results ob- tained were evaluated prospectively in our urol- ogy clinic. Pre-op urine culture, intraoperative renal puncture culture, stone washing culture and stone cultures were examined. Demographic characteristics of the patients and microorgan- isms breeding in all cultures were evaluated. In addition, the ratios of MDRI in microorganisms breeding in all four cultures and the factors that may cause it were evaluated statistically.
Results: Our study consisted of 155 patients, 78 of whom were male and 77 were female, with a mean age of 40.8 ± 16.6 years. While 88 of these patients’ stones were on the left and 67 were on the right, the average stone load of the patients was calculated to be 3827,74 ± 1932,07 mm3. When the urine culture results of the patients were examined, it was found that middle stream urine culture was observed in 34 patients (21.9%) in intrarenal urine culture in 57 patients (36.7%), in 24 patients (15.4%) in stone washing culture and in 21 patients in stone culture (13.5%). A total of eight patients (5.1%) had fever (0.69%) in only one of these patients. No statistically sig- nificant difference was found between the four cultures for the MDRI study (p> 0.05). When the factors that may cause MDRI are examined; we found that only male gender was a risk factor for MDRI.
Conclusion: It was concluded that male sex in patients with PCNL due to renal calculi is a risk factor for MDRI and that no additional treat- ment is needed when appropriate prophylactic and empirical treatment of MDRI is considered as a risk factor for postoperative fever and sepsis.
Keywords: Kidney stone; urinary infection; percutaneous nephrolithotomy