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Original Research

Multitrakt Percutaneous Nephrolithotripsy Versus Sandwich Therapy for Coralliform Kidney Stones


1 Universty of Health and Science Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey

2 Ankara University School of Medicine


DOI : 10.33719/yud.582475
New J Urol. 2019; 14 (2): 71-80

Abstract

Objective: Percutaneous nephrolitho- tomy (PNL) and extracorporeal shock wave lithotripsy (SWL) are performed in treatment of kidney stone disease for a long period be- side the other treatment methods. Since 1987 PNL procedure has been used successfully and safely in our clinic for treatment of kidney stones. We aimed to compare the success rates of multitract access and sandwich therapies (PNL+SWL+PNL) in staghorn kidney stones performed in four years period.

Material and Methods: During last four years 462 patients underwent PNL pro- cedures in our clinic. 126 of the patients had staghorn kidney stones 23 of the patients (16male/7female) had multitract PNL while

16 (12male/4female) underwent sandwich therapy. We compare these two groups for postopertive early period and in 6th month success, major (bleeding and adjecent organ injury etc.) and minor (fever, urinary tract infections) complications, total hospitalizati- on period, additional treatment requirements and total operation duration.

Results: Statistically significant differen- ces were appearent between two groups while total hospitalization period (9,74±3,19 days in multitract PNL group and 22,12±10,19 days in sandwich therapy group), total operation duration (110,78±35,57 minutes in multit- ract PNL group and 176,87±31,51 minutes in sandwich therapy group)(p<0,001) and blood replacement volumes (1,86±1,63 IU in multitract PNL group and 3,37±1,89 IU in sandwich therapy group) (p<0,05).

The early postoperative period results (69,5% stone free rates, 17,4% ‘clinically insignificant residual fragments’ (CIRF) rates and 13,04% residual stone rates in in multitract PNL group and 62,5% stone free rates, 17,4% CIRF rates and 13,04% residual stone rates in days in sandwich therapy group) and in 6th month success findings were similar between two groups (p>0,05). Also additional treat- ment requirements, complication (major and minor) rates, stone analysis are compared and we did not find statistically significant differences between two groups (p>0,05).

Conclusion: PNL is successfull and safe treatment method of staghorn stones. It can be performed with multitract technique in one session or with sandwich therapy technique which can be com- bined with SWL due to conditions. Besides the blood replacement volumes, hospitalization period and the ooperation, the compari- son of these treatment modalities did not exhibit any significant differences for success and complication rates. Our outcomes are compatible with the literature.

Keywords: Kidney stone, Percutaneous nefrolitotomy, PNL, sandwich therapy, SWL

Objective: Percutaneous nephrolitho- tomy (PNL) and extracorporeal shock wave lithotripsy (SWL) are performed in treatment of kidney stone disease for a long period be- side the other treatment methods. Since 1987 PNL procedure has been used successfully and safely in our clinic for treatment of kidney stones. We aimed to compare the success rates of multitract access and sandwich therapies (PNL+SWL+PNL) in staghorn kidney stones performed in four years period.

Material and Methods: During last four years 462 patients underwent PNL pro- cedures in our clinic. 126 of the patients had staghorn kidney stones 23 of the patients (16male/7female) had multitract PNL while

16 (12male/4female) underwent sandwich therapy. We compare these two groups for postopertive early period and in 6th month success, major (bleeding and adjecent organ injury etc.) and minor (fever, urinary tract infections) complications, total hospitalizati- on period, additional treatment requirements and total operation duration.

Results: Statistically significant differen- ces were appearent between two groups while total hospitalization period (9,74±3,19 days in multitract PNL group and 22,12±10,19 days in sandwich therapy group), total operation duration (110,78±35,57 minutes in multit- ract PNL group and 176,87±31,51 minutes in sandwich therapy group)(p<0,001) and blood replacement volumes (1,86±1,63 IU in multitract PNL group and 3,37±1,89 IU in sandwich therapy group) (p<0,05).

The early postoperative period results (69,5% stone free rates, 17,4% ‘clinically insignificant residual fragments’ (CIRF) rates and 13,04% residual stone rates in in multitract PNL group and 62,5% stone free rates, 17,4% CIRF rates and 13,04% residual stone rates in days in sandwich therapy group) and in 6th month success findings were similar between two groups (p>0,05). Also additional treat- ment requirements, complication (major and minor) rates, stone analysis are compared and we did not find statistically significant differences between two groups (p>0,05).

Conclusion: PNL is successfull and safe treatment method of staghorn stones. It can be performed with multitract technique in one session or with sandwich therapy technique which can be com- bined with SWL due to conditions. Besides the blood replacement volumes, hospitalization period and the ooperation, the compari- son of these treatment modalities did not exhibit any significant differences for success and complication rates. Our outcomes are compatible with the literature.

Keywords: Kidney stone, Percutaneous nefrolitotomy, PNL, sandwich therapy, SWL


Abstract

Objective: Percutaneous nephrolitho- tomy (PNL) and extracorporeal shock wave lithotripsy (SWL) are performed in treatment of kidney stone disease for a long period be- side the other treatment methods. Since 1987 PNL procedure has been used successfully and safely in our clinic for treatment of kidney stones. We aimed to compare the success rates of multitract access and sandwich therapies (PNL+SWL+PNL) in staghorn kidney stones performed in four years period.

Material and Methods: During last four years 462 patients underwent PNL pro- cedures in our clinic. 126 of the patients had staghorn kidney stones 23 of the patients (16male/7female) had multitract PNL while

16 (12male/4female) underwent sandwich therapy. We compare these two groups for postopertive early period and in 6th month success, major (bleeding and adjecent organ injury etc.) and minor (fever, urinary tract infections) complications, total hospitalizati- on period, additional treatment requirements and total operation duration.

Results: Statistically significant differen- ces were appearent between two groups while total hospitalization period (9,74±3,19 days in multitract PNL group and 22,12±10,19 days in sandwich therapy group), total operation duration (110,78±35,57 minutes in multit- ract PNL group and 176,87±31,51 minutes in sandwich therapy group)(p<0,001) and blood replacement volumes (1,86±1,63 IU in multitract PNL group and 3,37±1,89 IU in sandwich therapy group) (p<0,05).

The early postoperative period results (69,5% stone free rates, 17,4% ‘clinically insignificant residual fragments’ (CIRF) rates and 13,04% residual stone rates in in multitract PNL group and 62,5% stone free rates, 17,4% CIRF rates and 13,04% residual stone rates in days in sandwich therapy group) and in 6th month success findings were similar between two groups (p>0,05). Also additional treat- ment requirements, complication (major and minor) rates, stone analysis are compared and we did not find statistically significant differences between two groups (p>0,05).

Conclusion: PNL is successfull and safe treatment method of staghorn stones. It can be performed with multitract technique in one session or with sandwich therapy technique which can be com- bined with SWL due to conditions. Besides the blood replacement volumes, hospitalization period and the ooperation, the compari- son of these treatment modalities did not exhibit any significant differences for success and complication rates. Our outcomes are compatible with the literature.

Keywords: Kidney stone, Percutaneous nefrolitotomy, PNL, sandwich therapy, SWL

Objective: Percutaneous nephrolitho- tomy (PNL) and extracorporeal shock wave lithotripsy (SWL) are performed in treatment of kidney stone disease for a long period be- side the other treatment methods. Since 1987 PNL procedure has been used successfully and safely in our clinic for treatment of kidney stones. We aimed to compare the success rates of multitract access and sandwich therapies (PNL+SWL+PNL) in staghorn kidney stones performed in four years period.

Material and Methods: During last four years 462 patients underwent PNL pro- cedures in our clinic. 126 of the patients had staghorn kidney stones 23 of the patients (16male/7female) had multitract PNL while

16 (12male/4female) underwent sandwich therapy. We compare these two groups for postopertive early period and in 6th month success, major (bleeding and adjecent organ injury etc.) and minor (fever, urinary tract infections) complications, total hospitalizati- on period, additional treatment requirements and total operation duration.

Results: Statistically significant differen- ces were appearent between two groups while total hospitalization period (9,74±3,19 days in multitract PNL group and 22,12±10,19 days in sandwich therapy group), total operation duration (110,78±35,57 minutes in multit- ract PNL group and 176,87±31,51 minutes in sandwich therapy group)(p<0,001) and blood replacement volumes (1,86±1,63 IU in multitract PNL group and 3,37±1,89 IU in sandwich therapy group) (p<0,05).

The early postoperative period results (69,5% stone free rates, 17,4% ‘clinically insignificant residual fragments’ (CIRF) rates and 13,04% residual stone rates in in multitract PNL group and 62,5% stone free rates, 17,4% CIRF rates and 13,04% residual stone rates in days in sandwich therapy group) and in 6th month success findings were similar between two groups (p>0,05). Also additional treat- ment requirements, complication (major and minor) rates, stone analysis are compared and we did not find statistically significant differences between two groups (p>0,05).

Conclusion: PNL is successfull and safe treatment method of staghorn stones. It can be performed with multitract technique in one session or with sandwich therapy technique which can be com- bined with SWL due to conditions. Besides the blood replacement volumes, hospitalization period and the ooperation, the compari- son of these treatment modalities did not exhibit any significant differences for success and complication rates. Our outcomes are compatible with the literature.

Keywords: Kidney stone, Percutaneous nefrolitotomy, PNL, sandwich therapy, SWL