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Case Report

Paraganglioma of Urinary Bladder: A Case Report


1 Department of Medical Pathology, Health Sciences University Gazi Yasargil Training and Research Hospital, Diyarbakir, Turkey
2 Dicle University Faculty of Medicine, Department of Medical Pathology, Diyarbakir, Turkey 
3 Dicle University Faculty of Medicine, Department of Medical Pathology, Diyarbakir, Turkey


DOI : 10.33719/yud.2023;18-3-1287231
New J Urol. 2023;18(3):258-263.

Abstract

Objective: The majority of bladder lesions are papillary and/or flat-appearing urothelial neoplasms. Neoplasms other than urothelial tumors are extremely rare. Paragangliomas are rare catecholamine-releasing tumors of sympathetic ganglion or chromaffin cell origin. Approximately 10% of paragangliomas occur in the non-adrenal region, of which 10% are seen in the bladder and constitute 0.05% of all bladder tumors. About 10% of paraganglioma occur in extra-adrenal sites, of which, 10% are located in bladder wall accounting for 0.05% of all bladder tumors.

In a 42-year-old female patient, a mass on the anterolateral wall of the bladder, measuring 50x43 mm solid mass protruding into the lumen with necrotic center and increased vascularity on the periphery was reported. The specimens of the, transurethral resection bladder material obtained from an external center and our hospital were examined by pathology and diagnosed as paraganglioma. Because of its rarity and confusion with urothelial carcinoma, paraganglioma should always be recognized when dealing with bladder tumors.

Keywords: bladder -paraganglioma -extra adrenal
 


Abstract

Objective: The majority of bladder lesions are papillary and/or flat-appearing urothelial neoplasms. Neoplasms other than urothelial tumors are extremely rare. Paragangliomas are rare catecholamine-releasing tumors of sympathetic ganglion or chromaffin cell origin. Approximately 10% of paragangliomas occur in the non-adrenal region, of which 10% are seen in the bladder and constitute 0.05% of all bladder tumors. About 10% of paraganglioma occur in extra-adrenal sites, of which, 10% are located in bladder wall accounting for 0.05% of all bladder tumors.

In a 42-year-old female patient, a mass on the anterolateral wall of the bladder, measuring 50x43 mm solid mass protruding into the lumen with necrotic center and increased vascularity on the periphery was reported. The specimens of the, transurethral resection bladder material obtained from an external center and our hospital were examined by pathology and diagnosed as paraganglioma. Because of its rarity and confusion with urothelial carcinoma, paraganglioma should always be recognized when dealing with bladder tumors.

Keywords: bladder -paraganglioma -extra adrenal