Objective: The most common sexually transmitted disease amongst men is urethritis. Treatment failure can be prevented with the isolation of pathogens and appropriate antimicrobial therapy when antibiotic susceptibility is known. In our study of patients with urethral discharge, we aimed to determine the isolated pathogens and antibiotic sensitivity.
Materials and Methods: The results of patients with urethral discharge at our urology clinic between January 1st 2008 and May 31st 2010 were evaluated retrospectively. Urethral swab samples taken from patients were studied for bacteria identification and their antibiotic susceptibility.
Results: During the study period, 248 patients between the ages of 18-42 in our hospital were followed. Pathogens were determined in 131 (16%) out of the 816 tests requested from patients. 16 different microorganisms were identified in the 94 patients (37.9%) (one or more cultures from each), who were detected with reproduction. The distribution of 131 pathogens determined: U. urealyticum % 38,9, C. trachomatis % 21,4, coagulase-negative staphylococci 7.6%, and Staphylococcus haemolyticus 6.9%. Besides, simultaneous reproductions of U. urealyticum and M. hominis in seven patients, U. urealyticum and S. haemolyticus in three patients, U. urealyticum and S. aureus in one patient, and S. agalactiae and Klebsiella spp. in another patient were detected. It was determined that the most effective (100%) antibiotic on isolated Mycoplasmas and Ureaplasmas was doxycycline.
Conclusion: While it was not possible to determine the pathogens in most patients with urethral discharge, Ureaplasma and Chlamidya were the most common amongst the pathogens identified. It would be appropriate to determine the antimicrobials for treatment according to results of culture antibiogram. Empirical treatment is inevitable when pathogens could not be identified.
Key Words: Urethritis, Ureaplasma, Chlamidya.
Abstract
Objective: The most common sexually transmitted disease amongst men is urethritis. Treatment failure can be prevented with the isolation of pathogens and appropriate antimicrobial therapy when antibiotic susceptibility is known. In our study of patients with urethral discharge, we aimed to determine the isolated pathogens and antibiotic sensitivity.
Materials and Methods: The results of patients with urethral discharge at our urology clinic between January 1st 2008 and May 31st 2010 were evaluated retrospectively. Urethral swab samples taken from patients were studied for bacteria identification and their antibiotic susceptibility.
Results: During the study period, 248 patients between the ages of 18-42 in our hospital were followed. Pathogens were determined in 131 (16%) out of the 816 tests requested from patients. 16 different microorganisms were identified in the 94 patients (37.9%) (one or more cultures from each), who were detected with reproduction. The distribution of 131 pathogens determined: U. urealyticum % 38,9, C. trachomatis % 21,4, coagulase-negative staphylococci 7.6%, and Staphylococcus haemolyticus 6.9%. Besides, simultaneous reproductions of U. urealyticum and M. hominis in seven patients, U. urealyticum and S. haemolyticus in three patients, U. urealyticum and S. aureus in one patient, and S. agalactiae and Klebsiella spp. in another patient were detected. It was determined that the most effective (100%) antibiotic on isolated Mycoplasmas and Ureaplasmas was doxycycline.
Conclusion: While it was not possible to determine the pathogens in most patients with urethral discharge, Ureaplasma and Chlamidya were the most common amongst the pathogens identified. It would be appropriate to determine the antimicrobials for treatment according to results of culture antibiogram. Empirical treatment is inevitable when pathogens could not be identified.
Key Words: Urethritis, Ureaplasma, Chlamidya.