Objective: To investigate the prevalence of detrusor overac-tivity (DOA) concomitant to clinical benign prostate hyperplasia (BPH) and the relationship between some of the characteristic pa-rameters of BPH and the presence of concomitant DOA.
Materials and methods: This is a prospective analysis of 100 patients with a previous diagnosis of clinical BPH and no previous diagnosis of DOA. All patients were urodynamically evaluated and divided in two groups (Group 1: Pure BPH, Group 2: BPH with DOA). Some characteristic parameters of BPH were statistically compared between two groups.
Results: Filling cystometry results showed that 52 men (%52) had detrusor overactivity. In pressure-flow studies, obstructive voiding findings were determined in all patients. In univariate analysis, patients with DOA were significantly older, had lower Q max, higher creatinine, higher IPSS and OAB V-8 scores. On the other hand, multivariate analysis revealed that only age, IPSS, and OAB V-8 scores were independently associated with the presence of DOA.
Conclusion: In BPH patients, the presence of concomitant DOA is independently associated with only age, IPSS, and OAB- V8 scores. It will be very logical to consider concomitant DOA and especially to routinely use OAB questionnaire in the management of patients with previous diagnosis of clinical BPH and ongoing LUTS despite receiving prolonged medical treatment.
Key words: Benign prostate hyperplasia, detrusor overactivity, lower urinary tract symptoms, urodynamic testing.
Abstract
Objective: To investigate the prevalence of detrusor overac-tivity (DOA) concomitant to clinical benign prostate hyperplasia (BPH) and the relationship between some of the characteristic pa-rameters of BPH and the presence of concomitant DOA.
Materials and methods: This is a prospective analysis of 100 patients with a previous diagnosis of clinical BPH and no previous diagnosis of DOA. All patients were urodynamically evaluated and divided in two groups (Group 1: Pure BPH, Group 2: BPH with DOA). Some characteristic parameters of BPH were statistically compared between two groups.
Results: Filling cystometry results showed that 52 men (%52) had detrusor overactivity. In pressure-flow studies, obstructive voiding findings were determined in all patients. In univariate analysis, patients with DOA were significantly older, had lower Q max, higher creatinine, higher IPSS and OAB V-8 scores. On the other hand, multivariate analysis revealed that only age, IPSS, and OAB V-8 scores were independently associated with the presence of DOA.
Conclusion: In BPH patients, the presence of concomitant DOA is independently associated with only age, IPSS, and OAB- V8 scores. It will be very logical to consider concomitant DOA and especially to routinely use OAB questionnaire in the management of patients with previous diagnosis of clinical BPH and ongoing LUTS despite receiving prolonged medical treatment.
Key words: Benign prostate hyperplasia, detrusor overactivity, lower urinary tract symptoms, urodynamic testing.