Objective: To evaluate pathological results of patients who underwent transrectal ultraso-nography guided prostate biopsy and rebiopsy of patients with atypical small acinar proliferation (ASAP) and high grade intraepithelial neoplasia (HGPIN).
Material and Methods: We evaluated 1763 pathology results of transrectal ultrasonography guided prostate biopsy between October 2007 and April 2013. Of these 1763 pathology results, 73 of patients were underwent re biopy and 6 of them were underwent third biopsy. Total of 338 patients without a proper pathology result and results with no PSA value were ruled out from study. Pathology results included into the study were performed on 1337 patients. Patients were grouped in to 6 groups according to their first pathology results.
Results: According to the first pathology re-sult 25.4% of patients were enrolled into adeno-cancer group. High grade intraepithelial neoplasia more than one focus, ASAP and ASAP+HGPIN were seen 0.5%, 7.1% and 0.2% of patients, res-pectively. Re biopsy of these 3 groups detected adenocancer 40%,31% and 50% in orderly.
Conclusion: Patients with pathology results of HGPIN and/or ASAP should be followed up carefuly and patients should be informed about the importance of rebiopsy.
Key words: ASAP, HGPIN, prostate biopsy
Abstract
Objective: To evaluate pathological results of patients who underwent transrectal ultraso-nography guided prostate biopsy and rebiopsy of patients with atypical small acinar proliferation (ASAP) and high grade intraepithelial neoplasia (HGPIN).
Material and Methods: We evaluated 1763 pathology results of transrectal ultrasonography guided prostate biopsy between October 2007 and April 2013. Of these 1763 pathology results, 73 of patients were underwent re biopy and 6 of them were underwent third biopsy. Total of 338 patients without a proper pathology result and results with no PSA value were ruled out from study. Pathology results included into the study were performed on 1337 patients. Patients were grouped in to 6 groups according to their first pathology results.
Results: According to the first pathology re-sult 25.4% of patients were enrolled into adeno-cancer group. High grade intraepithelial neoplasia more than one focus, ASAP and ASAP+HGPIN were seen 0.5%, 7.1% and 0.2% of patients, res-pectively. Re biopsy of these 3 groups detected adenocancer 40%,31% and 50% in orderly.
Conclusion: Patients with pathology results of HGPIN and/or ASAP should be followed up carefuly and patients should be informed about the importance of rebiopsy.
Key words: ASAP, HGPIN, prostate biopsy