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Original Research

Evaluation of the agrement between histopathology results of transrectal biopsy and radical prostatectomy specimens in patıent wıth radical prostatectomy


1 Sağlık Bilimleri Üniversitesi Bağcılar SUAM Üroloji Kliniği, İstanbul, Türkiye

2 Hitit Üniversitesi, Üroloji ABD, Çorum, Türkiye

3 İlyas Çokay Devlet Hastanesi Üroloji Kliniği, İstanbul, Türkiye

4 Sağlık Bilimleri Üniversitesi Bakırköy SUAM Üroloji Kliniği, İstanbul, Türkiye


DOI :
New J Urol. 2018; 13 (3): 40-45

Abstract

Aim: To investigate the effects of age, serum prostate-specific antigen (PSA) level, body mass index (BMI), prostate volume, post-prostatec-tomy tumor volume, positive core number and day from biopsy to the surgery on concordance between transrectal ultrasound guided prostate biopsy and post-prostatectomy biopsy results in terms of  International Society of Urological Pathology (ISUP) and D’ Amico classification systems scores.

Materials and Method: Between 2008-2015, 167 men underwent radical prostatec-tomy were included to the study. Patients with changed and same ISUP and D’ Amico classifi-cation scores after prostatectomy were classified. Age, serum PSA level, BMI, prostate volume, post-prostatectomy tumor volume, positive core number and day from biopsy to the surgery were compared between the groups.

Results: Mean age and PSA levels were 64.16±5.68 and 9.2±6.61 ng/ml, respectively. Mean age, BMI, prostate volume and day from biopsy to the surgery were similar between the patients with changed and same post-prosta-tectomy ISUP scores. Mean PSA level, post-prostatectomy tumor volume and positive core number were significantly increased in patients with changed post-prostatectomy ISUP scores (p=0.008, p=0.043 and p=0.011, respectively). Mean PSA level, age, prostate volume, post-prostatectomy tumor volume, positive core number and day from biopsy to the surgery were similar between the patients with changedand same post-prostatectomy D’ Amico scores. Only, mean BMI was significantly increased in patients with changed post-prostatectomy D’ Amico scores (p=0.034).

Conclusion: Curative treatment approaches could be best option in patients with elevated serum PSA levels, higher BMI and increased positive core number because higher probability of high grade disease.

Keywords: prostate cancer, International Society of Urological Pa-thology (ISUP),D’ Amico classification systems scores, prostate specific antigen, transrectal prostate needle biopsy


Abstract

Aim: To investigate the effects of age, serum prostate-specific antigen (PSA) level, body mass index (BMI), prostate volume, post-prostatec-tomy tumor volume, positive core number and day from biopsy to the surgery on concordance between transrectal ultrasound guided prostate biopsy and post-prostatectomy biopsy results in terms of  International Society of Urological Pathology (ISUP) and D’ Amico classification systems scores.

Materials and Method: Between 2008-2015, 167 men underwent radical prostatec-tomy were included to the study. Patients with changed and same ISUP and D’ Amico classifi-cation scores after prostatectomy were classified. Age, serum PSA level, BMI, prostate volume, post-prostatectomy tumor volume, positive core number and day from biopsy to the surgery were compared between the groups.

Results: Mean age and PSA levels were 64.16±5.68 and 9.2±6.61 ng/ml, respectively. Mean age, BMI, prostate volume and day from biopsy to the surgery were similar between the patients with changed and same post-prosta-tectomy ISUP scores. Mean PSA level, post-prostatectomy tumor volume and positive core number were significantly increased in patients with changed post-prostatectomy ISUP scores (p=0.008, p=0.043 and p=0.011, respectively). Mean PSA level, age, prostate volume, post-prostatectomy tumor volume, positive core number and day from biopsy to the surgery were similar between the patients with changedand same post-prostatectomy D’ Amico scores. Only, mean BMI was significantly increased in patients with changed post-prostatectomy D’ Amico scores (p=0.034).

Conclusion: Curative treatment approaches could be best option in patients with elevated serum PSA levels, higher BMI and increased positive core number because higher probability of high grade disease.

Keywords: prostate cancer, International Society of Urological Pa-thology (ISUP),D’ Amico classification systems scores, prostate specific antigen, transrectal prostate needle biopsy

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