Objective: In this study we aimed to evaluate the bacterial diversity of causative agent of urinary tract infection and current antibiotic susceptibility in our hospital.
Materials and Methods: In this study we eva-luated 403 patients whose 3244 urine culture with microbial growth that applied Sakarya Education and Research hospital between January and De-cember 2012. The patients that reproduction of culture in samples accepted contamination and under the age of 18 excluded from the study.
Results: The mean age was 49(18-72). 58% of patients were male, 42% were female. 403 micro-organisms reproducted in the cultures. In 366 cul-tures gram negative microroganism and in 37 cul-tures gram positive microorganisms ısolated. The most frequently isolated agent is E.coli bacterium with 77.6%. When the antibiotic susceptibility of the samples analyzed, 40.1% were found resistant to ampicillin-sulbactam, 36.5% ciprofloxacin, 31.4% trimethroprim-sulfamethoxazole, 20.3% cefuroxime, 16.2% ceftriaxone and 13.9% were found resistant to gentamicin.
Conclusion: Due to inappropriate medication in the treatment of urinary tract infections, resis-tance to antibiotics recently dramatic increases in basic seen. For empirical therapy it is important to know the regional patterns of resistance. Periodic monitoring of resistance patterns in our hospital has changed our approach to empirical therapy.
Key Words: Urinary Tract; Infection; Antibi-otics
Abstract
Objective: In this study we aimed to evaluate the bacterial diversity of causative agent of urinary tract infection and current antibiotic susceptibility in our hospital.
Materials and Methods: In this study we eva-luated 403 patients whose 3244 urine culture with microbial growth that applied Sakarya Education and Research hospital between January and De-cember 2012. The patients that reproduction of culture in samples accepted contamination and under the age of 18 excluded from the study.
Results: The mean age was 49(18-72). 58% of patients were male, 42% were female. 403 micro-organisms reproducted in the cultures. In 366 cul-tures gram negative microroganism and in 37 cul-tures gram positive microorganisms ısolated. The most frequently isolated agent is E.coli bacterium with 77.6%. When the antibiotic susceptibility of the samples analyzed, 40.1% were found resistant to ampicillin-sulbactam, 36.5% ciprofloxacin, 31.4% trimethroprim-sulfamethoxazole, 20.3% cefuroxime, 16.2% ceftriaxone and 13.9% were found resistant to gentamicin.
Conclusion: Due to inappropriate medication in the treatment of urinary tract infections, resis-tance to antibiotics recently dramatic increases in basic seen. For empirical therapy it is important to know the regional patterns of resistance. Periodic monitoring of resistance patterns in our hospital has changed our approach to empirical therapy.
Key Words: Urinary Tract; Infection; Antibi-otics