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Research Article

Association of Apelin Levels with Lymph Node Invasion and Clinical Progression in Obese Patients Undergoing Radical Prostatectomy for Prostate Cancer


1 Department of Urology, Istanbul Medeniyet University, School of Medicine, Istanbul, Türkiye
2 Department of Urology, Nizip State Hospital, Gaziantep, Türkiye


DOI : 10.33719/nju1603293
New J Urol. 2025;20(2):71-78.

Abstract

Leiomyomas are benign mesenchymal smooth muscle tumours. Pure leiomyoma of prostate is very rare. Here we presented a case of 77-year-old men who admitted to hospital with symptoms of infravesical obstruction. The per-rectal and ultra- sonographic examination revealed an enlarged prostate. Open prostatectomy procedure was per- formed. The prostate weigh was 172 gr in gross pathological examination and solid nodular lesion was observed on the cut surface of the prostate. Mi- croscopically, the lesion was composed of spindle cell proliferation, without nuclear atypia, necrosis and mitotic activity. Radiological methods are in- adequate for determination of the biological nature of such nodules. Therefore, histopathology is very important for excluding of malignancy. Open pros- tatectomy is an effective method for both treatment and diagnostic purposes.

Keywords: Prostate, mesenchymal tumour, spindle cell proliferation, nodule.
 


Abstract

Leiomyomas are benign mesenchymal smooth muscle tumours. Pure leiomyoma of prostate is very rare. Here we presented a case of 77-year-old men who admitted to hospital with symptoms of infravesical obstruction. The per-rectal and ultra- sonographic examination revealed an enlarged prostate. Open prostatectomy procedure was per- formed. The prostate weigh was 172 gr in gross pathological examination and solid nodular lesion was observed on the cut surface of the prostate. Mi- croscopically, the lesion was composed of spindle cell proliferation, without nuclear atypia, necrosis and mitotic activity. Radiological methods are in- adequate for determination of the biological nature of such nodules. Therefore, histopathology is very important for excluding of malignancy. Open pros- tatectomy is an effective method for both treatment and diagnostic purposes.

Keywords: Prostate, mesenchymal tumour, spindle cell proliferation, nodule.