Objective: Transrectal ultrasound guided prostate needle biopsy has become standard procedure in prostate cancer diagnosis. We aimed to investigate the efficacy of transrectal ultrasound guided prostate needle biopsy on prostatic diseases and review histopathological outcomes.
Materials and Methods: Six hundred and forty-three patients were evaluated in our cli-nic. Transrectal ultrasound guided prostate needle biopsies for suspicious prostate cancer diagnosis were evaluated retrospectively.
Results: Mean age of patients was 66.09±7.65, mean serum prostate spesific an-tigene value 46.69±410.72 ng/mL and digital rectal examination positivity was 175(27.2%). Of the biopsy results 313(48.7%) were benign prostatic hypertrophy, 139(21.6%) were carci-noma of the prostate, 114(17.8%) were pros-tatitis, 51(7.9%) were prostatic intraepithelial neoplasia and 26(4%) were atypical small aci-nar proliferation of prostate, respectively. Mean serum prostate spesific antigene level in carci-noma of the prostate group was statistically sig-nificantly higher in other groups. Prostate can-cer incidence was statistically significantly high in the older than 65 years group than younger than 65 years group.
Conclusions: Patients with elevated prosta-te spesific antigene and digital rectal examina-tion findings should be considered as high risk group and should be followed closely in terms of prostate cancer and transrectal ultrasound guided prostate needle biopsy is safe and effec-tive procedure for this group of patients who have extend from benign to malign conditions.
Key Words: Pathology, Prostate, Prostate Spesific Antigene
Abstract
Objective: Transrectal ultrasound guided prostate needle biopsy has become standard procedure in prostate cancer diagnosis. We aimed to investigate the efficacy of transrectal ultrasound guided prostate needle biopsy on prostatic diseases and review histopathological outcomes.
Materials and Methods: Six hundred and forty-three patients were evaluated in our cli-nic. Transrectal ultrasound guided prostate needle biopsies for suspicious prostate cancer diagnosis were evaluated retrospectively.
Results: Mean age of patients was 66.09±7.65, mean serum prostate spesific an-tigene value 46.69±410.72 ng/mL and digital rectal examination positivity was 175(27.2%). Of the biopsy results 313(48.7%) were benign prostatic hypertrophy, 139(21.6%) were carci-noma of the prostate, 114(17.8%) were pros-tatitis, 51(7.9%) were prostatic intraepithelial neoplasia and 26(4%) were atypical small aci-nar proliferation of prostate, respectively. Mean serum prostate spesific antigene level in carci-noma of the prostate group was statistically sig-nificantly higher in other groups. Prostate can-cer incidence was statistically significantly high in the older than 65 years group than younger than 65 years group.
Conclusions: Patients with elevated prosta-te spesific antigene and digital rectal examina-tion findings should be considered as high risk group and should be followed closely in terms of prostate cancer and transrectal ultrasound guided prostate needle biopsy is safe and effec-tive procedure for this group of patients who have extend from benign to malign conditions.
Key Words: Pathology, Prostate, Prostate Spesific Antigene