Objective: We aim to compare the antibiog-ram sensitivity results and the isolated bacteria in urine cultures of patients who applied to our clinic with symptoms of urinary tract infection and imaging surveys detected kidney stones or no kidney stones.
Material and Methods: Urine samples gathered from patients between the age of 15 and 50 who visited our urology polyclinic with symptoms of urinary tract infection between November 2010 and June 2013. Microbiologi-cal aspects of these samples were evaluated in the Central Microbiology Lab. Urine samples that isolated bacteria which more than 105 colo-nies in performed urine culture of patients with scanning the database of laboratory information system were included in the study. Patients were separated into two groups: those with kidney sto-nes (Group I) and those without kidney stones (Group II). Identification of the microorganisms and their sensitivity to antibiotics were measu-red with fully automatic (VITEK®2, Biomerieux, France) device.
Results: Urine culture results of 2882 pati-ents were analyzed retrospectively. The samples of 441 (15.3%) patients demonstrated a prolife-ration of bacteria colonies above 105. 119 pati-ents (27%) had kidney stones (Group I) and 322 (73%) patients did not (Group II).Among the pa-tients with kidney stones, some microorganisms were isolated in a higher percentage (Table I) and the high ratios of Acinetobacter spp. and Entero-bacter spp. isolations were statistically significant (p<0.01). Among the patients without kidney stones, certain microorganisms were isolated inhigher ratios (Table I) and high ratios of E. coli. And Klebsiella spp. isolations were statistically significant (p<0.01). The variations in the antibiotic sensitivities of Enterobactericeae microorganisms was not statistically significant. In the comparison of antibiotic sensiti-vity ratios of Enterococcus type bacteria, the high ratios of resistance was found statistically significant for ciprofloxacin and gentamicin in patients with kidney stones (p<0.01). The other isolated micro-organisms were not in sufficient numbers and thus, their ratios of sensitivity to antibiotics were not compared.
Conclusion: In this study, it is observed that certain microor-ganisms such as Acinetobacter that lead to antibiotic-resistant in-fections were isolated in higher percentages in patients with kidney stones. Also, urine cultures need to be produced in order to detect the microorganisms and evaluate the sensitivity tests before and af-ter the completion of antimicrobial treatment.
Key Words: kidney stones, urine culture, sensitivity to antibi-otics
Abstract
Objective: We aim to compare the antibiog-ram sensitivity results and the isolated bacteria in urine cultures of patients who applied to our clinic with symptoms of urinary tract infection and imaging surveys detected kidney stones or no kidney stones.
Material and Methods: Urine samples gathered from patients between the age of 15 and 50 who visited our urology polyclinic with symptoms of urinary tract infection between November 2010 and June 2013. Microbiologi-cal aspects of these samples were evaluated in the Central Microbiology Lab. Urine samples that isolated bacteria which more than 105 colo-nies in performed urine culture of patients with scanning the database of laboratory information system were included in the study. Patients were separated into two groups: those with kidney sto-nes (Group I) and those without kidney stones (Group II). Identification of the microorganisms and their sensitivity to antibiotics were measu-red with fully automatic (VITEK®2, Biomerieux, France) device.
Results: Urine culture results of 2882 pati-ents were analyzed retrospectively. The samples of 441 (15.3%) patients demonstrated a prolife-ration of bacteria colonies above 105. 119 pati-ents (27%) had kidney stones (Group I) and 322 (73%) patients did not (Group II).Among the pa-tients with kidney stones, some microorganisms were isolated in a higher percentage (Table I) and the high ratios of Acinetobacter spp. and Entero-bacter spp. isolations were statistically significant (p<0.01). Among the patients without kidney stones, certain microorganisms were isolated inhigher ratios (Table I) and high ratios of E. coli. And Klebsiella spp. isolations were statistically significant (p<0.01). The variations in the antibiotic sensitivities of Enterobactericeae microorganisms was not statistically significant. In the comparison of antibiotic sensiti-vity ratios of Enterococcus type bacteria, the high ratios of resistance was found statistically significant for ciprofloxacin and gentamicin in patients with kidney stones (p<0.01). The other isolated micro-organisms were not in sufficient numbers and thus, their ratios of sensitivity to antibiotics were not compared.
Conclusion: In this study, it is observed that certain microor-ganisms such as Acinetobacter that lead to antibiotic-resistant in-fections were isolated in higher percentages in patients with kidney stones. Also, urine cultures need to be produced in order to detect the microorganisms and evaluate the sensitivity tests before and af-ter the completion of antimicrobial treatment.
Key Words: kidney stones, urine culture, sensitivity to antibi-otics