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Original Research

The effect of patient’s age on oncologic and survival results in patients undergoing radical cystectomy due to muscle invasive bladder cancer


İzmir Bozyaka Eğitim ve Araştırma Hastanesi, İzmir


DOI :
New J Urol. 2018; 13 (2): 48-52

Abstract

Purpose: To investigate the effect of age on oncologic and survival results in patients under-going radical cystectomy due to muscle invasive bladder cancer.

Material and Method: We reviewed the data of 178 patients who underwent radical cystectomy  between January 2006 and Novem-ber 2016 due to bladder cancer in our clinic. Finally 147 patients who underwent radical cystectomy due to muscle-invasive bladder can-cer were included in the study. Patients were di-vided into two groups as; patient age  ≤ 70 years (Group 1) and > 70 years (Group 2). Then we compared the groups in terms of preoperative data, oncological outcomes and survival fin-dings.

Results: There were 101 and 46 patients in group 1 and group 2 respectively. There was no statistically significant difference between the two groups in terms of gender, preoperative T stage, tumor grade, preoperative hydronephro-sis and precence of carcinoma in situ (CIS). Pre-operative ASA score was higher in the elderly group (Group 2) (p = 0.007). Postoperative data showed that the presence of variant histology, T stage, upstaging, tumor grade, lymph node metastasis, positive surgical margins were simi-lar between the two groups. There was no sta-tistically significant difference between the two groups in terms of overall survival and cancer-specific survival.

Conclusion : There was no statistically sig-nificant difference between oncologic and survi-val findings  between  ≤ 70 years and > 70 years old patients who underwent radical cystectomy due to muscle invasive bladder cancer.

Keywords: bladder cancer; age; radical cystectomy


Abstract

Purpose: To investigate the effect of age on oncologic and survival results in patients under-going radical cystectomy due to muscle invasive bladder cancer.

Material and Method: We reviewed the data of 178 patients who underwent radical cystectomy  between January 2006 and Novem-ber 2016 due to bladder cancer in our clinic. Finally 147 patients who underwent radical cystectomy due to muscle-invasive bladder can-cer were included in the study. Patients were di-vided into two groups as; patient age  ≤ 70 years (Group 1) and > 70 years (Group 2). Then we compared the groups in terms of preoperative data, oncological outcomes and survival fin-dings.

Results: There were 101 and 46 patients in group 1 and group 2 respectively. There was no statistically significant difference between the two groups in terms of gender, preoperative T stage, tumor grade, preoperative hydronephro-sis and precence of carcinoma in situ (CIS). Pre-operative ASA score was higher in the elderly group (Group 2) (p = 0.007). Postoperative data showed that the presence of variant histology, T stage, upstaging, tumor grade, lymph node metastasis, positive surgical margins were simi-lar between the two groups. There was no sta-tistically significant difference between the two groups in terms of overall survival and cancer-specific survival.

Conclusion : There was no statistically sig-nificant difference between oncologic and survi-val findings  between  ≤ 70 years and > 70 years old patients who underwent radical cystectomy due to muscle invasive bladder cancer.

Keywords: bladder cancer; age; radical cystectomy

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